Welcome to Editor’s Review, a series where your trusted Stylevana editor dives deep into the latest and greatest of skincare, makeup and beauty to offer you a bite-sized review. Our goal is to break down a formula for you and get you up to speed about everything you need to know about it, helping you decide whether it’s worth a spot in your routine or not. Whether you’ve got questions about the formula, the texture, the finish, we’ve got you covered.

There’s nothing quite like the meteoric rise of PDRN within the beauty world. This impressive ingredient, originally derived from Salmon DNA and later vegan sources, completely took over the 2025 trend reports, touted to be a savior ingredient for dry, damaged and sagging skin. From dermatological treatments and injectables to accessible skincare products for daily use, PDRN has cemented its status as a must-have within any routine.

We can’t discuss the innovation and development of PDRN skincare without mentioning Rejuran, the skin rejuvenation treatment that utilizes bio-compatible polynucleotides (PNs) derived from Salmon. This treatment forms the basis for the Rejuran cosmetics line, which offers potent c-PDRN® (a patented PDRN technology) throughout its skincare range, allowing users to enjoy the skin-perfecting benefits of this highly sought-after ingredient without needing a dermatologist appointment.

The number one item from the Rejuran skincare collection? Truth be told we can’t give you just one straight answer, but the Dual Effect Ampoule is undeniably one of the brand’s top selling products. There are countless reviews waxing poetic about its visible brightening effects, soothing properties and lightweight texture, but is this booster really worth it? Let your STYLEVANA editor get to the bottom of things and help you decide if you should add the Rejuran Dual Effect Ampoule to cart.

 

Rejuran - Dual Effect Ampoule

 

Formula: Each and every one of Rejuran’s skincare products exclusively features c-PDRN®, a patented form of Salmon-derived PDRN that has been developed to effectively penetrate the skin without the need for injections. This key ingredient, extracted with DNA Optimization Technology (D.O.T.), works within the dermis to encourage collagen production for a plumped effect, provide relief to damaged skin and enhance overall skin health. It’s also clinically proven to treat signs of aging, restore skin after acne scarring and protect the complexion against environmental factors. Seriously, what can’t it do?

Joining c-PDRN® are a host of other ingredients with stellar track records: Ceramide NP for strengthening the skin barrier; Squalane for moisturizing effects and refining skin texture; and Niacinamide for supporting skin radiance and minimizing the appearance of pores. The formula restores the skin from the inside out with Triple Absorption Technology to up skin firmness and luminosity. It’s a true gem that targets many skin concerns at once, especially suitable for recovering the skin post-treatment.

 

Rejuran - Dual Effect Ampoule

 

Texture and finish: On the watery-to-viscous spectrum, the Dual Effect Ampoule lands somewhere between “right in the middle” and distinctly watery. It has a light body, but it’s the kind of watery texture that slowly glides down your skin when you apply it. Because of that, it practically pats itself in with almost no effort. The finish? A bright, dewy complexion that feels fresh and weightless—no greasiness, no heaviness.

 

Rejuran - Dual Effect Ampoule

 

Packaging: The golden bottle doesn’t just offer your run-of-the-mill dropper. It features a pull-up plunger that dispenses product in a hygienic way, plus you can get accurate with how much product you’re dispensing at a time so you’re not wasting a single drop. The formula is housed in a glass bottle that is weighty and luxurious, living up to Rejuran’s premium branding as well as safeguarding the ampoule from expiring prematurely.

 

Rejuran - Dual Effect Ampoule

 

Other things to note: The ampoule is free of fragrance and other harmful additives. It can be used in both the AM and PM, and its benefits are amplified when used in conjunction with other Rejuran products.

 

Rejuran - Dual Effect Ampoule

 

Editor’s POV: It may be hard to believe that the effects of a skincare product could compare to those of a skin treatment, and while I’ve never experienced Rejuran injectables myself, the results of using the Dual Effect Ampoule make me feel like I can skip out on them. After every use my skin is noticeably brighter, smoother and plumper, as if I’ve just come out of a facial; the lightweight texture makes it so nice to incorporate into my daily routine because it doesn’t clash with my other products. One thing to note is that very dry complexions may not find this ampoule hydrating enough, and may need to add an additional layer of hydration to stave off dryness. All in all, a very dependable formula I can see a lot of skin types reaching for, and I’ll certainly continue to stock up on it whenever I’m running low.

 

Rejuran - Dual Effect Ampoule

Rejuran - Dual Effect Ampoule

Courtesy of Korean Skincare Brand - Rejuran

More Rejuran Bestsellers

 
 

Rejuran - Turnover Ampoule Rejuran - Turnover Active Cream Enhanced Rejuran - Moisture Treatment Mask

 

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